PLA2G7 antibody (AA 301-441) (Biotin)

Catalog No. ABIN686724

Product Details anti-PLA2G7 Antibody (Biotin)

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Binding Specificity: AA 301-441

Reactivity: Human, Mouse, Rat, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G7 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Pig, Rabbit, Rat

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAFAH2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PLA2G7

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Alternative Name: PAFAH (Lp-PLA2 Products)

Synonyms: LDL-PLA2 antibody, LP-PLA2 antibody, PAFAD antibody, PAFAH antibody, Lp-PLA2 antibody, PAF-AH antibody, R75400 antibody, zgc:77563 antibody, phospholipase A2 group VII antibody, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) antibody, PLA2G7 antibody, Pla2g7 antibody, pla2g7 antibody

Background:

Synonyms: PAFAD, PAFAH, LP-PLA2, LDL-PLA2, Platelet-activating factor acetylhydrolase, PAF acetylhydrolase, 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, gVIIA-PLA2, LDL-associated phospholipase A2, LDL-PLA(2), PAF 2-acylhydrolase, PLA2G7

Background: Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.

Gene ID: 7941

UniProt: Q13093

Pathways: Peptide Hormone Metabolism