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EPOR antibody (AA 301-450)

Name: EPOR antibody (AA 301-450)
SKU: ABIN686347
Price: 384.62 USD
Availability: InStock

EPOR Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat brain tissue labeled withAnti-EPOR Polyclonal Antibody (ABIN686347), Unconjugated at 1:100 followed by conjugation to the secondary antibody, (SP-0023), and DAB staining (EPOR antibody (AA 301-450))

IHC

Formalin-fixed and paraffin embedded rat lung tissue labeled with Anti-EPOR Polyclonal Antibody (ABIN686347), Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (EPOR antibody (AA 301-450))

IHC

Formalin-fixed and paraffin embedded rat brain tissue labeled withAnti-EPOR Polyclonal Antibody , Unconjugated at 1:100 followed by conjugation to the secondary antibody, (SP-0023), and DAB staining (EPOR antibody (AA 301-450))

IHC (p)

Formalin-fixed and paraffin embedded rat lung tissue labeled with Anti-EPOR Polyclonal Antibody , Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (EPOR antibody (AA 301-450))

IHC (p)

4 images

(2 references)

Catalog No. ABIN686347

Datasheet as PDF

Target

EPOR (Erythropoietin Receptor (EPOR))
Binding Specificity
15

11

8

7

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 301-450
Reactivity
109

45

42

9

5

4

3

3

2

2

2

1

1
Human, Mouse, Rat
Host
93

18

5

1
Rabbit
Compatible Secondaries
Clonality
100

16

1
Polyclonal
Conjugate
64

10

7

5

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This EPOR antibody is un-conjugated
Application
86

39

23

21

20

15

13

13

10

5

5

4

3

2

2

1

1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Human, Mouse, Rat

Predicted Reactivity

Dog,Cow,Horse

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human EPOR

Isotype

IgG
anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibody
EPOR Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 3D10 unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 470-504), (C-Term) antibody
EPOR Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB50846 unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 45-244) antibody
EPOR Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibody
EPOR Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3F6 unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 274-508) antibody
EPOR Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 320-506) antibody
EPOR Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) antibody
EPOR Reactivity: Human FACS, cELISA Host: Mouse Monoclonal VP-2E8 unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 1-508) antibody
EPOR Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) (pTyr368) antibody
EPOR Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) (pTyr426) antibody
EPOR Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Li, Chen, Shao, Tang, Chen, Chen, Xu: "Oxidative stress induces the decline of brain EPO expression in aging rats." in: Experimental gerontology, Vol. 83, pp. 89-93, (2016) (PubMed).

Zhong, Zhang: "Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations." in: Molecular medicine reports, Vol. 15, Issue 1, pp. 228-234, (2016) (PubMed).
Target

EPOR (Erythropoietin Receptor (EPOR))

Alternative Name

EPOR

Background

Synonyms: EPO-R, Erythropoietin receptor, EPOR
Background: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

Gene ID

2057

UniProt

P19235

Pathways

JAK-STAT Signaling