NCOR2 antibody (AA 2201-2525)

Catalog No. ABIN686302

Product Details anti-NCOR2 Antibody

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Binding Specificity: AA 2201-2525

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOR2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCOR2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NCOR2

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Alternative Name: Ncor2 (NCOR2 Products)

Synonyms: CTG26 antibody, N-CoR2 antibody, SMAP270 antibody, SMRT antibody, SMRTE antibody, SMRTE-tau antibody, TNRC14 antibody, TRAC antibody, TRAC-1 antibody, TRAC1 antibody, N-CoR antibody, SMRTe antibody, NCOR2 antibody, gb:be017685 antibody, si:bz71m17.2 antibody, smrt antibody, ctg26 antibody, smrte antibody, trac1 antibody, tnrc14 antibody, trac-1 antibody, smrte-tau antibody, nuclear receptor corepressor 2 antibody, nuclear receptor co-repressor 2 antibody, NCOR2 antibody, Ncor2 antibody, ncor2 antibody

Background:

Synonyms: Nuclear receptor corepressor 2, N-CoR2, Silencing mediator of retinoic acid and thyroid hormone receptor, SMRT, Thyroid- retinoic-acid-receptor-associated corepressor, T3 receptor-associating factor, TRAC, CTG repeat protein 26, SMAP270.

Background: NCoR2_Nuclear receptor corepressor 2_mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors.

Gene ID: 9612

UniProt: Q9Y618

Pathways: Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha