MC1 Receptor antibody (AA 271-317) (FITC)

Catalog No. ABIN686294

Product Details anti-MC1 Receptor Antibody (FITC)

Target: MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

Binding Specificity: AA 271-317

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC1 Receptor antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse MC1R

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-MC1 Receptor antibody (FITC) (ABIN686294)

Bekeschus, Rödder, Fregin, Otto, Lippert, Weltmann, Wende, Schmidt, Gandhirajan: "Toxicity and Immunogenicity in Murine Melanoma following Exposure to Physical Plasma-Derived Oxidants." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4396467, (2018) (PubMed).

Target Details for MC1 Receptor

Target: MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

Abstract: MC1R Products

Synonyms: CMM5 antibody, MSH-R antibody, SHEP2 antibody, Mshra antibody, Tob antibody, e antibody, MC1-R antibody, MSHR antibody, mc1r antibody, MC1R antibody, TUBB3 antibody, melanocortin 1 receptor antibody, melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) antibody, MC1R antibody, Mc1r antibody, mc1r antibody, mc1r_par1 antibody

Background:

Synonyms: Mshra, Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R, Mc1r

Background: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

Gene ID: 17199

UniProt: Q01727

Pathways: cAMP Metabolic Process, Feeding Behaviour