KLF6 antibody
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- Target See all KLF6 Antibodies
- KLF6 (Kruppel-Like Factor 6 (KLF6))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KLF6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human KLF6
- Isotype
- IgG
- Top Product
- Discover our top product KLF6 Primary Antibody
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- Application Notes
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WB: 1:100-1000, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- KLF6 (Kruppel-Like Factor 6 (KLF6))
- Alternative Name
- Klf6/Pac1 (KLF6 Products)
- Background
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Synonyms: Kruppel-like factor 6, B cell derived protein 1, BCD1, COPEB, Core promoter element-binding protein, CPBP, GC rich sites binding factor GBF, Krueppel-like factor 6, Proto-oncogene BCD1, Transcription factor Zf9, Zf9, CBA1, DKFZp686N0199, GBF, PAC1, ST12, KLF6_HUMAN.
Background: KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene.
- Gene ID
- 1316
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