MAP2 antibody (AA 1-120)

Catalog No. ABIN685567

Product Details anti-MAP2 Antibody

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Binding Specificity: AA 1-120

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Pig, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MAP2 antibody (ABIN685567)

Lu, Ben, Xiao, Peng, Zhang: "AMP-activated protein kinase activation in mediating phenylalanine-induced neurotoxicity in experimental models of phenylketonuria." in: Journal of inherited metabolic disease, (2018) (PubMed).

Usui, Sakurai, Kawasaki, Ohama, Yamawaki, Sato: "Establishment of a novel three-dimensional primary culture model for hippocampal neurogenesis." in: Physiological reports, Vol. 5, Issue 12, (2017) (PubMed).

Wang, Jing, Song, Xing: "Neuroprotective effects of Wnt/β-catenin signaling pathway against Aβ -induced tau protein over-phosphorylation in PC12 cells." in: Biochemical and biophysical research communications, Vol. 471, Issue 4, pp. 628-32, (2016) (PubMed).

Zuo, Wang, Li, Lin, Duan, Qi, Li, Sun, Wu: "Existence of glia mitigated ketamine-induced neurotoxicity in neuron-glia mixed cultures of neonatal rat cortex and the glia-mediated protective effect of 2-PMPA." in: Neurotoxicology, Vol. 44, pp. 218-30, (2014) (PubMed).

Gu, Huang, Shen, Gao, Ding, Wu, Guo: "Early activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampi." in: Journal of neuroinflammation, Vol. 10, pp. 109, (2013) (PubMed).

Huang, Xu, Cao, Cao, Zhang: "The expression of FOXJ1 in neurogenesis after transient focal cerebral ischemia." in: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, Vol. 40, Issue 3, pp. 403-9, (2013) (PubMed).

Target Details for MAP2

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Alternative Name: MAP2/MAP-2a.b.c (MAP2 Products)

Synonyms: MAP2A antibody, MAP2B antibody, MAP2C antibody, MAP2R antibody, Mtap2 antibody, MAP-2 antibody, Mtap-2 antibody, xmap2 antibody, MGC53131 antibody, a730034c02 antibody, zgc:103474 antibody, zgc:113974 antibody, microtubule associated protein 2 antibody, microtubule-associated protein 2 antibody, microtubule associated protein 2 S homeolog antibody, MAP2 antibody, Map2 antibody, map2.S antibody, map2 antibody

Background:

Synonyms: MAP2A, MAP2B, MAP2C, Microtubule-associated protein 2, MAP-2, MAP2

Background: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

Gene ID: 4133

UniProt: P11137