TSG101 antibody (AA 4-120)
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- Target See all TSG101 Antibodies
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Binding Specificity
- AA 4-120
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Reactivity
- Human, Mouse, Rat, Fish
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TSG101 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Fish, Human, Mouse, Rat
- Predicted Reactivity
- Dog,Cow,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Tsg101
- Isotype
- IgG
- Top Product
- Discover our top product TSG101 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
- Alternative Name
- Tsg101 (TSG101 Products)
- Background
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Synonyms: TSG10, VPS23, Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101
Background: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
- Gene ID
- 7251
- UniProt
- Q99816
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