C3AR1 antibody (AA 401-482)

Catalog No. ABIN682213

Product Details anti-C3AR1 Antibody

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Binding Specificity: AA 401-482

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C3AR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C3a Receptor/C3aR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-C3AR1 antibody (ABIN682213)

Schäfer, Rasras, Ormenisan, Amslinger, Enzmann, Jägle, Pauly: "Complement Factor H-Related 3 Enhanced Inflammation and Complement Activation in Human RPE Cells." in: Frontiers in immunology, Vol. 12, pp. 769242, (2022) (PubMed).

Shinjyo, de Pablo, Pekny, Pekna: "Complement Peptide C3a Promotes Astrocyte Survival in Response to Ischemic Stress." in: Molecular neurobiology, (2015) (PubMed).

Target Details for C3AR1

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Alternative Name: C3a Receptor (C3AR1 Products)

Synonyms: C3AR antibody, C3a-R antibody, c3ar1 antibody, AZ3B antibody, HNFAG09 antibody, C3a anaphylatoxin chemotactic receptor antibody, complement C3a receptor 1 antibody, complement component 3a receptor 1 antibody, c3ar1 antibody, C3AR1 antibody, C3ar1 antibody

Background:

Synonyms: AZ3B, C3AR, HNFAG09, C3a anaphylatoxin chemotactic receptor, C3a-R, C3AR1, C3R1

Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Gene ID: 719

UniProt: Q16581

Pathways: Complement System