PARD3 antibody (AA 1201-1356)
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- Target See all PARD3 Antibodies
- PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))
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Binding Specificity
- AA 1201-1356
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PARD3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PARD-3
- Isotype
- IgG
- Top Product
- Discover our top product PARD3 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))
- Alternative Name
- PARD-3 (PARD3 Products)
- Synonyms
- ASIP antibody, Baz antibody, PAR3 antibody, PAR3alpha antibody, PARD-3 antibody, PARD3A antibody, SE2-5L16 antibody, SE2-5LT1 antibody, SE2-5T2 antibody, Par3 antibody, AA960621 antibody, AI256638 antibody, D8Ertd580e antibody, PAR-3 antibody, Pard3a antibody, asip antibody, bazooka antibody, par-3 antibody, par3 antibody, pard3 antibody, par-3 family cell polarity regulator antibody, partitioning defective 3 homolog antibody, par-3 family cell polarity regulator alpha, b antibody, par-3 family cell polarity regulator S homeolog antibody, PARD3 antibody, Pard3 antibody, LOC100551156 antibody, LOC100473914 antibody, pard3 antibody, pard3ab antibody, pard3.S antibody
- Background
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Synonyms: Baz, ASIP, PAR3, PARD-3, PARD3A, SE2-5T2, PPP1R118, SE2-5L16, SE2-5LT1, PAR3alpha, Partitioning defective 3 homolog, PAR-3, Atypical PKC isotype-specific-interacting protein, CTCL tumor antigen se2-5, PAR3-alpha, PARD3, PAR3A
Background: Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
- Gene ID
- 56288
- UniProt
- Q8TEW0
- Pathways
- Cell-Cell Junction Organization
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