LPAR1 antibody (AA 281-364)

Catalog No. ABIN681103

Product Details anti-LPAR1 Antibody

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Binding Specificity: AA 281-364

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPAR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EDG2/LPAR1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-LPAR1 antibody (ABIN681103)

Chen, Zhang, Deng, Liu, Yang, Wu, Yu: "Lysophosphatidic acid directly induces macrophage-derived foam cell formation by blocking the expression of SRBI." in: Biochemical and biophysical research communications, Vol. 491, Issue 3, pp. 587-594, (2017) (PubMed).

Target Details for LPAR1

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Alternative Name: LPAR1 (LPAR1 Products)

Synonyms: EDG2 antibody, GPR26 antibody, Gpcr26 antibody, LPA1 antibody, Mrec1.3 antibody, VZG1 antibody, edg-2 antibody, rec.1.3 antibody, vzg-1 antibody, Edg2 antibody, EDG-2 antibody, 5031439C20 antibody, AI326300 antibody, Kdt2 antibody, lpA1 antibody, edg2 antibody, si:dz22b13.1 antibody, si:dz46m7.1 antibody, zgc:92157 antibody, LPA receptor 1-A antibody, LPA-1-A antibody, gpr26 antibody, lpa1 antibody, lpa1r antibody, lpa1r1 antibody, lpar1 antibody, lpar1-a antibody, lpar1-b antibody, vzg1 antibody, xLPA1-1 antibody, LPA receptor 1-B antibody, LPA-1-B antibody, edg2-A antibody, xLPA1-2 antibody, xlpa1R antibody, lysophosphatidic acid receptor 1 antibody, lysophosphatidic acid receptor 1 S homeolog antibody, lysophosphatidic acid receptor 1 L homeolog antibody, LPAR1 antibody, Lpar1 antibody, lpar1 antibody, lpar1.S antibody, lpar1.L antibody

Background:

Synonyms: EDG2, LPA1, VZG1, GPR26, edg-2, vzg-1, Gpcr26, Mrec1.3, rec.1.3, Lysophosphatidic acid receptor 1, LPA receptor 1, LPA-1, Lysophosphatidic acid receptor Edg-2, LPAR1

Background: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.

Gene ID: 1902

UniProt: Q92633

Pathways: Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration