Claudin 4 antibody (AA 21-120)

Catalog No. ABIN680743

Product Details anti-Claudin 4 Antibody

Target: Claudin 4 (CLDN4)

Binding Specificity: AA 21-120

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLDN4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Claudin 4 antibody (ABIN680743)

Wang, Chen, Liang, Yan, Lin, Liu, Luo, Huang, Li, Liu, Tang: "Notch inhibition promotes fetal liver stem/progenitor cells differentiation into hepatocytes via the inhibition of HNF-1?." in: Cell and tissue research, Vol. 357, Issue 1, pp. 173-84, (2014) (PubMed).

Target Details for Claudin 4

Target: Claudin 4 (CLDN4)

Alternative Name: Claudin 4 (CLDN4 Products)

Synonyms: CPE-R antibody, CPER antibody, CPETR antibody, CPETR1 antibody, WBSCR8 antibody, hCPE-R antibody, Cep-r antibody, Cpetr antibody, Cpetr1 antibody, CLDN4 antibody, cper antibody, cpe-r antibody, cpetr antibody, cpetr1 antibody, hcpe-r antibody, wbscr8 antibody, claudin 4 antibody, claudin 4 L homeolog antibody, CLDN4 antibody, Cldn4 antibody, cldn4 antibody, cldn4.L antibody

Background:

Synonyms: CPER, CPE-R, CPETR, CPETR1, WBSCR8, hCPE-R, Claudin-4, Clostridium perfringens enterotoxin receptor, CPE-receptor, Williams-Beuren syndrome chromosomal region 8 protein, CLDN4

Background: Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact made up of network of strands that act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.

Gene ID: 1364

UniProt: O14493

Pathways: Hepatitis C