PITX3 antibody (AA 231-302) (Biotin)

Catalog No. ABIN679990

Product Details anti-PITX3 Antibody (Biotin)

Target: PITX3 (Pituitary Homeobox 3 (PITX3))

Binding Specificity: AA 231-302

Reactivity: Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PITX3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Cow, Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PITX3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PITX3

Target: PITX3 (Pituitary Homeobox 3 (PITX3))

Alternative Name: PITX3 (PITX3 Products)

Synonyms: CTPP4 antibody, CTRCT11 antibody, PTX3 antibody, pitx3 antibody, Ptx3 antibody, ak antibody, zgc:109716 antibody, pitx3-A antibody, xPitx3 antibody, paired like homeodomain 3 antibody, paired-like homeodomain 3 antibody, paired like homeodomain 3 L homeolog antibody, paired-like homeodomain transcription factor 3 antibody, paired-like homeodomain transcription factor Pitx3 antibody, PITX3 antibody, Pitx3 antibody, pitx3.L antibody, pitx3 antibody

Background:

Synonyms: Homeobox protein PITX 3, Homeobox protein PITX3, MGC12766, Paired like homeodomain transcription factor 3, Paired-like homeodomain transcription factor 3, Pituitary homeobox 3, PITX 3, Pitx3, PITX3_HUMAN, PTX 3, PTX3.

Background: The transcription factor PITX3 is expressed selectively in the midbrain and regulates the differentiation and survival of dopaminergic neurons. Lack of this factor results in a degeneration similar to that seen in Parkinson's disease. PITX3 is also important in eye developement, mutations of the PITX3 gene have been associated with a familial form of cataracts.

Molecular Weight: 30-32kDa

Gene ID: 5309