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HBV PreS1,PreS2 antibody (Biotin)

HBV PreS1,PreS2 Reactivity: Hepatitis B Virus (HBV) WB, ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN679510
  • Target See all HBV PreS1,PreS2 products
    HBV PreS1,PreS2 (Hepatitis B Virus PreS1/PreS2 Protein (HBV PreS1,PreS2))
    Reactivity
    • 15
    • 3
    Hepatitis B Virus (HBV)
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HBV PreS1,PreS2 antibody is conjugated to Biotin
    Application
    Western Blotting (WB), ELISA
    Cross-Reactivity
    Virus
    Cross-Reactivity (Details)
    Hepatitis B virus ay/ad
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from HBSAG_HBVD2 sub. ayw pre S1/S2 protein
    Isotype
    IgG
  • Application Notes
    WB 1:100-1000
    IHC-P 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    HBV PreS1,PreS2 (Hepatitis B Virus PreS1/PreS2 Protein (HBV PreS1,PreS2))
    Abstract
    HBV PreS1,PreS2 Products
    Target Type
    Viral Protein
    Background

    Synonyms: Hepatitis B, HBSAG_HBVD2, HBSAG_HBVC5, Large envelope protein, Large surface protein, L glycoprotein, Major surface antigen, Large S protein, L-HBsAg, LHB

    Background: Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.

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