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ARHGEF2 antibody (pSer886)

ARHGEF2 Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN678563
  • Target See all ARHGEF2 Antibodies
    ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))
    Binding Specificity
    • 14
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer886
    Reactivity
    • 60
    • 30
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 54
    • 7
    • 2
    Rabbit
    Clonality
    • 50
    • 13
    Polyclonal
    Conjugate
    • 35
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF2 antibody is un-conjugated
    Application
    • 45
    • 19
    • 14
    • 14
    • 10
    • 8
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Arhgef2 around the phosphorylation site of Ser886
    Isotype
    IgG
    Top Product
    Discover our top product ARHGEF2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))
    Alternative Name
    GEF H1 (ARHGEF2 Products)
    Synonyms
    MGC82333 antibody, MGC86214 antibody, MGC75855 antibody, AA408978 antibody, GEF antibody, GEF-H1 antibody, GEFH1 antibody, LFP40 antibody, Lbcl1 antibody, Lfc antibody, P40 antibody, mKIAA0651 antibody, GEF-H1/LFC antibody, Rho/Rac guanine nucleotide exchange factor 2 antibody, Rho/Rac guanine nucleotide exchange factor 2 S homeolog antibody, rho/rac guanine nucleotide exchange factor (GEF) 2 antibody, ARHGEF2 antibody, arhgef2.S antibody, arhgef2 antibody, Arhgef2 antibody
    Background

    Synonyms: GEF H1phospho S886, Arhgef2Ser886, Lbcl1, Lfc, mKIAA0651, AA408978, ARHG2, ARHGEF 2, ARHGEF-2, ARHGEF2, GEF, GEF H1, GEF-H1, GEFH1, LFP40, MGC95068, P40, Prolerating cell nucleolar antigen p40, Protein GEF-H1, rho/rac guanine nucleotide exchange factor GEF 2, rho/rac guanine nucleotide exchange factor 2, rho/rac guanine nucleotide exchange factor.

    Background: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.

    Gene ID
    9181
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
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