NPPA antibody (AA 124-151)

Catalog No. ABIN676928

Product Details anti-NPPA Antibody

Target: NPPA (Natriuretic Peptide A (NPPA))

Binding Specificity: AA 124-151

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANP:124-151/153

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-NPPA antibody (ABIN676928)

Straub, Ehrenstein, Günther, Rauch, Trendafilova, Boschiero, Grifka, Fleck: "Increased extracellular water measured by bioimpedance and by increased serum levels of atrial natriuretic peptide in RA patients-signs of volume overload." in: Clinical rheumatology, (2016) (PubMed).

Target Details for NPPA

Target: NPPA (Natriuretic Peptide A (NPPA))

Alternative Name: ANP (NPPA Products)

Synonyms: anp antibody, ANF antibody, ANP antibody, Pnd antibody, RATANF antibody, ATFB6 antibody, CDD-ANF antibody, PND antibody, NPPA antibody, Anf antibody, atrial natriuretic peptide antibody, natriuretic peptide A antibody, natriuretic peptide type A antibody, anp antibody, nppa antibody, NPPA antibody, Nppa antibody

Background:

Synonyms: ANF, ANP, CDD, CDP, PND, ATFB6, ATRST2, CDD-ANF, Natriuretic peptides A, Cardiodilatin, Cardiodilatin-related peptide, Prepronatriodilatin, NPPA

Background: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

Gene ID: 4878

UniProt: P01160