LAMA3 antibody (AA 2701-2800) (HRP)

Catalog No. ABIN676082

Product Details anti-LAMA3 Antibody (HRP)

Target: LAMA3 (Laminin, alpha 3 (LAMA3))

Binding Specificity: AA 2701-2800

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMA3 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LAMA3

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LAMA3

Target: LAMA3 (Laminin, alpha 3 (LAMA3))

Alternative Name: LAMA3/Laminin 5 alpha 3 (LAMA3 Products)

Synonyms: LAMA3 antibody, BM600 antibody, E170 antibody, LAMNA antibody, LOCS antibody, lama3a antibody, Lama3B antibody, [a]3B antibody, laminin subunit alpha 3 antibody, laminin subunit alpha-3 antibody, laminin, alpha 3 antibody, LAMA3 antibody, LOC100401798 antibody, LOC100484669 antibody, lama3 antibody, Lama3 antibody

Background:

Synonyms: E170, LOCS, BM600, LAMNA, Laminin subunit alpha-3, Epiligrin 170 kDa subunit, Epiligrin subunit alpha, Kalinin subunit alpha, Laminin-5 subunit alpha, Laminin-6 subunit alpha, Laminin-7 subunit alpha, Nicein subunit alpha, LAMA3

Background: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.

Gene ID: 3909

UniProt: Q16787