Kallikrein 14 antibody (AA 201-267)

Catalog No. ABIN676058

Product Details anti-Kallikrein 14 Antibody

Target: Kallikrein 14 (KLK14)

Binding Specificity: AA 201-267

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLK14

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Kallikrein 14

Target: Kallikrein 14 (KLK14)

Alternative Name: Kallikrein 14 (KLK14 Products)

Synonyms: GK14 antibody, KLK-L6 antibody, kallikrein related-peptidase 14 antibody, kallikrein related peptidase 14 antibody, Klk14 antibody, KLK14 antibody

Background:

Synonyms: KLK-L6, Kallikrein-14, hK14, Kallikrein-like protein 6, KLK14, KLKL6

Background: Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis.

Gene ID: 43847

UniProt: Q9P0G3

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling