PKC antibody (AA 371-388)

Catalog No. ABIN6757377

Product Details anti-PKC Antibody

Target: PKC (Protein Kinase C (PKC))

Binding Specificity: AA 371-388

Reactivity: Human, Mouse, Rat, Cow, Chicken, Dog, Guinea Pig, Monkey, Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Specificity: This immunoaffinity purified detects ~67-83kD proteins, corresponding to the apparent molecular masses of the different isoforms of PKC on SDS-PAGE immunoblots. This antibody is pan-specific and was designed to recognize all four cPKC isoforms (alpha, beta, gamma and delta). Species cross-reactivity: Human, mouse, rat, bovine, canine, chicken, guinea pig, monkey, porcine, rabbit and sheep.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (94%).

Purification: Protein A Column

Immunogen: A 19 residue synthetic peptide KKDVVIQDDDVESTMVEK(C) based on the human PKC alpha (residues 371-388) with a cysteine (C) residue added and the peptide coupled to KLH. The cysteine residue at position 381 of the original sequence was substituted with a ser.

Isotype: IgG

Application Details

Application Notes: ELISA, IP (12.5 µg/mL), WB (2 µg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Borate buffer saline, pH 8.2, 40% glycerol.

Target Details for PKC

Target: PKC (Protein Kinase C (PKC))

Alternative Name: PKC / Protein Kinase C (PKC Products)

Pathways: TCR Signaling, Regulation of G-Protein Coupled Receptor Protein Signaling, Interaction of EGFR with phospholipase C-gamma, Phototransduction