USP1 antibody (AA 701-785) (Biotin)

Catalog No. ABIN675580

Product Details anti-USP1 Antibody (Biotin)

Target: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Binding Specificity: AA 701-785

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human USP1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for USP1

Target: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Alternative Name: USP1 (USP1 Products)

Synonyms: usp1-a antibody, UBP antibody, ubiquitin specific peptidase 1 antibody, ubiquitin specific peptidase 1 S homeolog antibody, USP1 antibody, usp1.S antibody, Usp1 antibody

Background:

Synonyms: UBP, Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1, USP1, USP 1,USP-1

Background: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity.

Gene ID: 7398

UniProt: O94782