Vasopressin antibody

Catalog No. ABIN675488

Product Details anti-Vasopressin Antibody

Target: Vasopressin (AVP) (Arginine Vasopressin (AVP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vasopressin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADH (CYFQNCPRG-NH? (Disulfide bond 1,6)

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Vasopressin

Target: Vasopressin (AVP) (Arginine Vasopressin (AVP))

Alternative Name: ADH/AVP/ARVP (AVP Products)

Synonyms: ADH antibody, ARVP antibody, AVP-NPII antibody, AVRP antibody, VP antibody, 2610201A18Rik antibody, Akr1a4 antibody, Vp antibody, Vsp antibody, DI antibody, Vas antibody, Adh antibody, Adh1a antibody, Adh1c antibody, adh antibody, arvp antibody, avrp antibody, avp-npii antibody, copeptin antibody, vasotocin antibody, arginine vasopressin antibody, aldo-keto reductase family 1, member A1 (aldehyde reductase) antibody, alcohol dehydrogenase 1 (class I) antibody, AVP antibody, Akr1a1 antibody, Avp antibody, Adh1 antibody, avp antibody

Background:

Synonyms: Antidiuretic Hormone, Arginine Vasopressin, ADH, Arginine vasopressin neurophysin II, ARVP, AVP, AVP NPII, AVRP, Vasopressin neurophysin 2 copeptin precursor, Vasopressin neurophysin II copeptin, VP.

Background: Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria.

Gene ID: 551

UniProt: P01185

Pathways: cAMP Metabolic Process