LYVE1 antibody (AA 231-318)

Catalog No. ABIN674799

Product Details anti-LYVE1 Antibody

Target: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Binding Specificity: AA 231-318

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LYVE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse LYVE-1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-LYVE1 antibody (ABIN674799)

Merigo, Brandolese, Facchin, Missaggia, Bernardi, Boschi, DIncà, Savarino, Sbarbati, Sturniolo: "Glucose transporter expression in the human colon." in: World journal of gastroenterology, Vol. 24, Issue 7, pp. 775-793, (2018) (PubMed).

Michurina, Ishenko, Klimontov, Archipov, Myakina, Cherepanova, Zavjalov, Koncevaya, Konenkov: "Linagliptin alleviates fatty liver disease in diabetic db/db mice." in: World journal of diabetes, Vol. 7, Issue 19, pp. 534-546, (2016) (PubMed).

Zhang, Li, Qian, Liu, Guo, Lin: "MTDH/AEG-1-based DNA vaccine suppresses metastasis and enhances chemosensitivity to paclitaxel in pelvic lymph node metastasis." in: Biomedicine & pharmacotherapy, Vol. 70, pp. 217-26, (2015) (PubMed).

Sun, Jia, Zhang, Liu, Zhang, Zhao: "A reproducible in-vivo model of lymphatic malformation in rats." in: Journal of comparative pathology, Vol. 145, Issue 4, pp. 390-8, (2011) (PubMed).

Target Details for LYVE1

Target: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Alternative Name: LYVE-1 (LYVE1 Products)

Synonyms: LYVE1 antibody, XLKD1 antibody, CRSBP-1 antibody, HAR antibody, LYVE-1 antibody, 1200012G08Rik antibody, Crsbp-1 antibody, Lyve-1 antibody, Xlkd1 antibody, lymphatic vessel endothelial hyaluronic receptor 1a antibody, lymphatic vessel endothelial hyaluronan receptor 1 antibody, lyve1a antibody, LYVE1 antibody, Lyve1 antibody

Background:

Synonyms: Xlkd1, Lyve-1, Crsbp-1, 1212G8Rik, Lymphatic vessel endothelial hyaluronic acid receptor 1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, Lyve1, Crsbp1

Background: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Gene ID: 114332

UniProt: Q8BHC0

Pathways: Glycosaminoglycan Metabolic Process