DYRK1A antibody (AA 22-71)

Catalog No. ABIN769026

Product Details anti-DYRK1A Antibody

Target: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Binding Specificity: AA 22-71

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Pig, Monkey, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYRK1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Mouse DYRK1A

Predicted Reactivity: Percent identity by BLAST analysis: Human, Bovine, Rabbit, Horse, Pig, Guinea pig (100%) Mouse, Dog (92%) Chicken (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa22-71 of mouse Dyrk1a (Q63470, NP_031916). Percent identity by BLAST analysis: Human, Gibbon, Galago, Marmoset, Rat, Elephant, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig (100%), Mouse, Dog, Zebra finch, Platypus (92%), Turkey, Chicken (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for DYRK1A

Target: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Alternative Name: DYRK / DYRK1A (DYRK1A Products)

Background: Name/Gene ID: DYRK1A
Subfamily: MNB/DYRK
Family: Protein Kinase

Synonyms: DYRK1A, DYRK1, DYRK, HMNB, HP86, MNB, MNB/DYRK protein kinase, MRD7, MNBH, Serine/threonine kinase MNB, Yak1-related kinase

Gene ID: 1859

NCBI Accession: NP_031916

UniProt: Q13627

Pathways: Mitotic G1-G1/S Phases