NLRP1 antibody (AA 323-372)

Catalog No. ABIN768983

Product Details anti-NLRP1 Antibody

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Binding Specificity: AA 323-372

Reactivity: Human, Mouse, Cow, Dog, Horse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human NLRP1 / NALP1

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse (100%) Rat (92%) Dog (85%) Bovine (84%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa323-372 of human NLRP1 (Q9C000, NP_001028225). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse (100%), Rat, Opossum (92%), Platypus, Rice (91%), Gorilla, Dog (85%), Galago, Elephant, Bovine, Rabbit, Horse, Pig, Guinea pig (84%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:62500.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for NLRP1

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Alternative Name: NALP1 / NLRP1 (NLRP1 Products)

Synonyms: CARD7 antibody, CIDED antibody, CLR17.1 antibody, DEFCAP antibody, DEFCAP-L/S antibody, NAC antibody, NALP1 antibody, PP1044 antibody, SLEV1 antibody, VAMAS1 antibody, NLR family pyrin domain containing 1 antibody, NLRP1 antibody, Nlrp1 antibody

Background: Name/Gene ID: NLRP1

Synonyms: NLRP1, CLR17.1, CARD7, DEFCAP, DEFCAP-L/S, NAC, SLEV1, VAMAS1, KIAA0926, NALP1, PP1044

Gene ID: 22861

NCBI Accession: NP_001028225

UniProt: Q9C000

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome