Adenylosuccinate Lyase antibody (AA 188-237)

Catalog No. ABIN6746728

Product Details anti-Adenylosuccinate Lyase Antibody

Target: Adenylosuccinate Lyase (ADSL)

Binding Specificity: AA 188-237

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenylosuccinate Lyase antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human ADSL

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Sheep, Bovine, Rabbit, Pig (92%) Mouse, Rat, Dog, Horse, Guinea pig (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa188-237 of human ADSL (P30566, NP_000017). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%), Sheep, Elephant, Bovine, Rabbit, Pig (92%), Galago, Mouse, Rat, Hamster, Dog, Bat, Horse, Guinea pig (85%), Opossum (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-Adenylosuccinate Lyase antibody (ABIN6746728)

Blumstein, Faundez, Nakatsu, Saito, Ohno, Kelly: "The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 20, pp. 8034-42, (2001) (PubMed).

Zhen, Jiang, Feng, Bright, Peden, Seymour, Novak, Elliott, Gorin, Robinson, Swank: "Abnormal expression and subcellular distribution of subunit proteins of the AP-3 adaptor complex lead to platelet storage pool deficiency in the pearl mouse." in: Blood, Vol. 94, Issue 1, pp. 146-55, (1999) (PubMed).

Ooi, Moreira, DellAngelica, Poy, Wassarman, Bonifacino: "Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet." in: The EMBO journal, Vol. 16, Issue 15, pp. 4508-18, (1997) (PubMed).

Target Details for Adenylosuccinate Lyase

Target: Adenylosuccinate Lyase (ADSL)

Alternative Name: ADSL / Adenylosuccinate Lyase (ADSL Products)

Synonyms: fi60b04 antibody, zgc:56061 antibody, wu:fi60b04 antibody, MGC53383 antibody, MGC69239 antibody, adsL antibody, F15C21.8 antibody, F15C21_8 antibody, AMPS antibody, ASASE antibody, ASL antibody, Adl antibody, Asl antibody, purB antibody, adenylosuccinate lyase antibody, adenylosuccinate lyase L homeolog antibody, adenylosuccinase; ASL antibody, Adenylosuccinate lyase antibody, L-Aspartase-like family protein antibody, ADSL antibody, adsl antibody, adsl.L antibody, ASL antibody, purB antibody, purB,adsL antibody, Mrub_2293 antibody, MMAH_RS02975 antibody, Arnit_0089 antibody, Mesil_1058 antibody, Slip_0597 antibody, Trad_2452 antibody, Deba_0652 antibody, Toce_1174 antibody, Acear_2324 antibody, Igag_0272 antibody, Saut_2156 antibody, Fbal_1996 antibody, Ndas_2434 antibody, Ilyop_0196 antibody, Lbys_2961 antibody, MFER_RS02920 antibody, Palpr_2192 antibody, Calni_0061 antibody, Ftrac_3746 antibody, AT1G36280 antibody, Olsu_1764 antibody, Adsl antibody

Background: Name/Gene ID: ADSL

Synonyms: ADSL, Adenylosuccinate lyase, AMPS, ASASE, Adenylosuccinase

Gene ID: 158

NCBI Accession: NP_000017

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process