ADRA1B antibody (AA 169-218)

Catalog No. ABIN6746727

Product Details anti-ADRA1B Antibody

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Binding Specificity: AA 169-218

Reactivity: Human, Mouse, Rat, Pig, Dog, Guinea Pig, Rabbit, Hamster, Horse, Monkey, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRA1B antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human ADRA1B

Predicted Reactivity: Percent identity by BLAST analysis: Mouse, Rat, Rabbit, Pig, Guinea pig (100%) Bovine (92%) Chicken (90%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa169-218 of human ADRA1B (P35368, NP_000670). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Dog, Bat, Rabbit, Horse, Pig, Guinea pig (100%), Bovine, Platypus (92%), Chicken (90%), Opossum (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-ADRA1B antibody (ABIN6746727)

Blumstein, Faundez, Nakatsu, Saito, Ohno, Kelly: "The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 20, pp. 8034-42, (2001) (PubMed).

Zhen, Jiang, Feng, Bright, Peden, Seymour, Novak, Elliott, Gorin, Robinson, Swank: "Abnormal expression and subcellular distribution of subunit proteins of the AP-3 adaptor complex lead to platelet storage pool deficiency in the pearl mouse." in: Blood, Vol. 94, Issue 1, pp. 146-55, (1999) (PubMed).

Ooi, Moreira, DellAngelica, Poy, Wassarman, Bonifacino: "Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet." in: The EMBO journal, Vol. 16, Issue 15, pp. 4508-18, (1997) (PubMed).

Target Details for ADRA1B

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Alternative Name: ADRA1B (ADRA1B Products)

Synonyms: LOC100136712 antibody, [a]1b antibody, ADRA1 antibody, ALPHA1BAR antibody, RDC5 antibody, alpha-1B adrenoceptor antibody, adrenoceptor alpha 1B antibody, adrenergic receptor, alpha 1b antibody, LOC100136712 antibody, ADRA1B antibody, Adra1b antibody

Background: Name/Gene ID: ADRA1B
Subfamily: Adrenergic
Family: GPCR

Synonyms: ADRA1B, Alpha 1b, Alpha-1B adrenergic receptor, Alpha-1b-adrenergic, Alpha-1B-adrenergic receptor, Alpha1b, Adrenoceptor alpha 1B, Alpha-1B adrenoreceptor, Alpha1B-AR, Alpha1beta-AR, ALPHA1BAR, ADRA1, Alpha-1B adrenoceptor, Alpha1b-adrenergic

Gene ID: 147

NCBI Accession: NP_000670

UniProt: P35368

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process