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IRGC antibody (AA 73-122)

IRGC Reactivity: Human, Rat, Mouse, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6746505
  • Target See all IRGC Antibodies
    IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
    Binding Specificity
    • 15
    • 6
    • 4
    • 2
    • 1
    AA 73-122
    Reactivity
    • 28
    • 20
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Dog
    Host
    • 28
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRGC antibody is un-conjugated
    Application
    • 28
    • 14
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    Mouse IRGC
    Predicted Reactivity
    Percent identity by BLAST analysis: Mouse (100%).
    Purification
    Immunoaffinity purified
    Immunogen
    Synthetic peptide located between aa73-122 of mouse Irgc1 (Q8C262, NP_950178). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Elephant, Panda, Dog (100%), Galago, Marmoset, Bovine, Bat, Horse, Pig, Guinea pig (92%).

    Type of Immunogen: Synthetic peptide
  • Application Notes
    Approved: WB (1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
    Comment

    Target Species of Antibody: Mouse

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Distilled water
    Concentration
    Lot specific
    Buffer
    Lyophilized from PBS with 2 % sucrose
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Bolton, Anthony, Perry: "Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo." in: Neuroscience, Vol. 86, Issue 4, pp. 1245-57, (1998) (PubMed).

    Fanning, Jameson, Jesaitis, Anderson: "The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton." in: The Journal of biological chemistry, Vol. 273, Issue 45, pp. 29745-53, (1998) (PubMed).

    Ando-Akatsuka, Saitou, Hirase, Kishi, Sakakibara, Itoh, Yonemura, Furuse, Tsukita: "Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues." in: The Journal of cell biology, Vol. 133, Issue 1, pp. 43-7, (1996) (PubMed).

  • Target
    IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
    Alternative Name
    IRGC1 / CINEMA (IRGC Products)
    Synonyms
    IFGGE antibody, CINEMA antibody, IRGC1 antibody, Iigp5 antibody, R30953_1 antibody, Ifgge antibody, Irgc1 antibody, RGD1311107 antibody, F630044M05Rik antibody, Gm1102 antibody, Gm474 antibody, Irgc antibody, immunity related GTPase cinema antibody, interferon-inducible GTPase 5-like antibody, immunity-related GTPase family, cinema antibody, immunity-related GTPase family, cinema 1 antibody, IRGC antibody, LOC476445 antibody, Irgc antibody, Irgc1 antibody
    Background
    Name/Gene ID: IRGC

    Synonyms: IRGC, CINEMA, Iigp5, IFGGE, Interferon inducible GTPase 5, IRGC1, Interferon-inducible GTPase 5, R30953_1
    Gene ID
    56269
    NCBI Accession
    NP_950178
    UniProt
    Q6NXR0
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