IRGC antibody (AA 73-122)
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- Target See all IRGC Antibodies
- IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
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Binding Specificity
- AA 73-122
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Reactivity
- Human, Rat, Mouse, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRGC antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- Mouse IRGC
- Predicted Reactivity
- Percent identity by BLAST analysis: Mouse (100%).
- Purification
- Immunoaffinity purified
- Immunogen
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Synthetic peptide located between aa73-122 of mouse Irgc1 (Q8C262, NP_950178). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Elephant, Panda, Dog (100%), Galago, Marmoset, Bovine, Bat, Horse, Pig, Guinea pig (92%).
Type of Immunogen: Synthetic peptide
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- Application Notes
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Approved: WB (1 μg/mL)
Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody. - Comment
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Target Species of Antibody: Mouse
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Distilled water
- Concentration
- Lot specific
- Buffer
- Lyophilized from PBS with 2 % sucrose
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
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Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo." in: Neuroscience, Vol. 86, Issue 4, pp. 1245-57, (1998) (PubMed).
: "The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton." in: The Journal of biological chemistry, Vol. 273, Issue 45, pp. 29745-53, (1998) (PubMed).
: "Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues." in: The Journal of cell biology, Vol. 133, Issue 1, pp. 43-7, (1996) (PubMed).
: "
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Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo." in: Neuroscience, Vol. 86, Issue 4, pp. 1245-57, (1998) (PubMed).
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- Target
- IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
- Alternative Name
- IRGC1 / CINEMA (IRGC Products)
- Synonyms
- IFGGE antibody, CINEMA antibody, IRGC1 antibody, Iigp5 antibody, R30953_1 antibody, Ifgge antibody, Irgc1 antibody, RGD1311107 antibody, F630044M05Rik antibody, Gm1102 antibody, Gm474 antibody, Irgc antibody, immunity related GTPase cinema antibody, interferon-inducible GTPase 5-like antibody, immunity-related GTPase family, cinema antibody, immunity-related GTPase family, cinema 1 antibody, IRGC antibody, LOC476445 antibody, Irgc antibody, Irgc1 antibody
- Background
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Name/Gene ID: IRGC
Synonyms: IRGC, CINEMA, Iigp5, IFGGE, Interferon inducible GTPase 5, IRGC1, Interferon-inducible GTPase 5, R30953_1 - Gene ID
- 56269
- NCBI Accession
- NP_950178
- UniProt
- Q6NXR0
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