LTC4S antibody (N-Term)

Catalog No. ABIN6746296

Product Details anti-LTC4S Antibody

Target: LTC4S (Leukotriene C4 Synthase (LTC4S))

Binding Specificity: N-Term

Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Bat, Monkey, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTC4S antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human LTC4S

Predicted Reactivity: Percent identity by BLAST analysis: Human, Dog, Bovine, Horse, Pig, Guinea pig (100%) Mouse, Rat (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide from N-Terminus of human LTC4S (Q16873, NP_665874). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Dog, Bovine, Bat, Horse, Pig, Guinea pig (100%), Mouse, Rat, Rabbit (92%), Galago (85%), Opossum, Zebrafish (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-LTC4S antibody (ABIN6746296)

Nishibe, Parry, Ishida, Aziz, Murray, Patel, Rahman, Strand, Saito, Saito, Hammond, Savidge, Mackman, Wijelath: "Oncostatin M promotes biphasic tissue factor expression in smooth muscle cells: evidence for Erk-1/2 activation." in: Blood, Vol. 97, Issue 3, pp. 692-9, (2001) (PubMed).

Pimentel-Muiños, Seed: "Regulated commitment of TNF receptor signaling: a molecular switch for death or activation." in: Immunity, Vol. 11, Issue 6, pp. 783-93, (2000) (PubMed).

Kieran, Blank, Logeat, Vandekerckhove, Lottspeich, Le Bail, Urban, Kourilsky, Baeuerle, Israël: "The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product." in: Cell, Vol. 62, Issue 5, pp. 1007-18, (1990) (PubMed).

Baeuerle, Baltimore: "Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor." in: Cell, Vol. 53, Issue 2, pp. 211-7, (1988) (PubMed).

Target Details for LTC4S

Target: LTC4S (Leukotriene C4 Synthase (LTC4S))

Alternative Name: LTC4S / LTC4 Synthase (LTC4S Products)

Synonyms: LTC4S antibody, ltc4s antibody, si:dkey-33h4.2 antibody, leukotriene C4 synthase antibody, leukotriene C4 synthase-like antibody, leukotriene C4 synthase, gene 1 antibody, Ltc4s antibody, LTC4S antibody, LTC4SL antibody, ltc4s.1 antibody, ltc4s antibody

Background: Name/Gene ID: LTC4S

Synonyms: LTC4S, Leukotriene C4 synthase, Leukotriene-C(4) synthase, LTC4 synthase

Gene ID: 4056

NCBI Accession: NP_665874

UniProt: Q16873

Pathways: Cellular Response to Molecule of Bacterial Origin