C8orf45 antibody (AA 431-480)

Catalog No. ABIN6746108

Product Details anti-C8orf45 Antibody

Target: C8orf45 (Chromosome 8 Open Reading Frame 45 (C8orf45))

Binding Specificity: AA 431-480

Reactivity: Human, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8orf45 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human C8orf45

Predicted Reactivity: Percent identity by BLAST analysis: Guinea pig (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa431-480 of human MCMDC2 (Q4G0Z9, NP_775789). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (100%), Monkey, Elephant, Rabbit, Horse (92%), Galago, Guinea pig (85%), Mouse, Rat (78%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-C8orf45 antibody (ABIN6746108)

Fulda, Debatin: "IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway." in: Oncogene, Vol. 21, Issue 15, pp. 2295-308, (2002) (PubMed).

Pedersen, Kitada, Schimmer, Kim, Zapata, Charboneau, Rassenti, Andreeff, Bennett, Sporn, Liotta, Kipps, Reed: "The triterpenoid CDDO induces apoptosis in refractory CLL B cells." in: Blood, Vol. 100, Issue 8, pp. 2965-72, (2002) (PubMed).

Target Details for C8orf45

Target: C8orf45 (Chromosome 8 Open Reading Frame 45 (C8orf45))

Alternative Name: MCMDC2 / C8orf45 (C8orf45 Products)

Synonyms: C8orf45 antibody, 6030422M02Rik antibody, minichromosome maintenance domain containing 2 antibody, MCMDC2 antibody, Mcmdc2 antibody

Background: Name/Gene ID: MCMDC2

Synonyms: MCMDC2, C8orf45

Gene ID: 157777

NCBI Accession: NP_775789

UniProt: Q4G0Z9