METTL3 antibody (C-Term)

Catalog No. ABIN6746084

Product Details anti-METTL3 Antibody

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Dog, Horse, Guinea Pig, Rabbit, Cow, Zebrafish (Danio rerio), Goat, Pig, Bat, Hamster, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL3 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human METTL3

Predicted Reactivity: Percent identity by BLAST analysis: Mouse, Dog, Bovine, Goat, Rabbit, Horse, Pig, Guinea pig (100%) Rat, Zebrafish (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide from C-Terminus of human METTL3 (Q86U44, NP_062826). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Goat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig (100%), Rat, Stickleback, Zebrafish (85%), Xenopus (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-METTL3 antibody (ABIN6746084)

Ginkel, Wordeman: "Expression and partial characterization of kinesin-related proteins in differentiating and adult skeletal muscle." in: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4143-58, (2000) (PubMed).

Yamazaki, Nakata, Okada, Hirokawa: "Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8443-8, (1996) (PubMed).

Target Details for METTL3

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Alternative Name: METTL3 / M6A (METTL3 Products)

Synonyms: fj82g07 antibody, wu:fj82g07 antibody, zgc:77093 antibody, IME4 antibody, M6A antibody, MT-A70 antibody, Spo8 antibody, 2310024F18Rik antibody, methyltransferase like 3 antibody, methyltransferase like 3 L homeolog antibody, methyltransferase-like 3 antibody, mettl3 antibody, mettl3.L antibody, METTL3 antibody, Mettl3 antibody

Background: Name/Gene ID: METTL3

Synonyms: METTL3, M6A, Methyltransferase like 3, MTA70, Spo8, IME4, MRNA m(6)A methyltransferase, MT-A70

Gene ID: 56339

NCBI Accession: NP_062826

UniProt: Q86U44