ING1 antibody (AA 301-422)

Catalog No. ABIN674514

Product Details anti-ING1 Antibody

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Binding Specificity: AA 301-422

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human inhibitor of growth gene 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Alternative Name: ING1/p33ING1b (ING1 Products)

Background:

Synonyms: inhibitor of growth gene 1, Growth inhibitor ING 1, Growth inhibitor ING1, Growth inhibitory protein ING 1, Growth inhibitory protein ING1, Homo sapiens growth inhibitor p33ING1 ING1 mRNA, complete cds, ING 1, Inhibitor of growth 1, Inhibitor of growth family member 1, Inhibitor of growth protein 1, p24ING1c, p33, p33 ING1, p33ING1, p33ING1b, p47, p47ING1a, Tumor suppressor ING 1, Tumor suppressor ING1.

Background: This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].

Gene ID: 3621

Pathways: Protein targeting to Nucleus, Autophagy