MSTN antibody (AA 281-375)

Catalog No. ABIN674469

Product Details anti-MSTN Antibody

Target: MSTN (Myostatin (MSTN))

Binding Specificity: AA 281-375

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSTN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Pig, Rat

Predicted Reactivity: Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GDF8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MSTN antibody (ABIN674469)

Qian, Tang, Yang, Wang, Cai, Jiang, Li, Jiang, Gao, Ma, Chen, An, Li, Cui: "Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs." in: Scientific reports, Vol. 5, pp. 14435, (2016) (PubMed).

Target Details for MSTN

Target: MSTN (Myostatin (MSTN))

Alternative Name: GDF8/MSTN (MSTN Products)

Synonyms: GDF-8 antibody, GDF8 antibody, gdf8 antibody, mstn antibody, zgc:109749 antibody, Gdf8 antibody, NV13143 antibody, MSLHP antibody, Cmpt antibody, myostatin antibody, myostatin b antibody, growth/differentiation factor 8 antibody, MSTN antibody, mstnb antibody, LOC5577632 antibody, BRAFLDRAFT_290840 antibody, Mstn antibody, mstn antibody

Background:

Synonyms: GDF8, MSLHP, Growth/differentiation factor 8, GDF-8, Myostatin, MSTN

Background: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Acts specifically as a negative regulator of skeletal muscle growth. [SUBUNIT] Homodimer, [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. Belongs to the TGF-beta family.

Gene ID: 2660

UniProt: O14793