Selectin E/CD62e antibody (AA 501-612)

Catalog No. ABIN674244

Product Details anti-Selectin E/CD62e Antibody

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Binding Specificity: AA 501-612

Reactivity: Human, Pig, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Selectin E/CD62e antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Pig, Rat

Predicted Reactivity: Dog,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse E-Selectin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Selectin E/CD62e antibody (ABIN674244)

Zhang, Wotzkow, Bongoni, Shaw-Boden, Siegrist, Taddeo, Blank, Hofstetter, Rieben: "Role of the plasma cascade systems in ischemia/reperfusion injury of bone." in: Bone, Vol. 97, pp. 278-286, (2017) (PubMed).

Naito, Hashimoto, Watanabe, Shirai, Takahashi, Kojima, Watanabe, Sato, Iso, Matsuyama, Suzuki, Ishibashi-Ueda, Watanabe: "Facilitatory effects of fetuin-A on atherosclerosis." in: Atherosclerosis, Vol. 246, pp. 344-51, (2016) (PubMed).

Chou, Lee, Chen, Hsu, Huang, Huang, Fang: "CD44 fucosylation on mesenchymal stem cell enhances homing and macrophage polarization in ischemic kidney injury." in: Experimental cell research, Vol. 350, Issue 1, pp. 91-102, (2016) (PubMed).

Tu, Cao, Zhong, Ding, Tang: "Atorvastatin protects against cerebral ischemia/reperfusion injury through anti-inflammatory and antioxidant effects." in: Neural regeneration research, Vol. 9, Issue 3, pp. 268-75, (2014) (PubMed).

Kong, Luo, Li, Zhou, He: "The anti-inflammatory effect of kaempferol on early atherosclerosis in high cholesterol fed rabbits." in: Lipids in health and disease, Vol. 12, pp. 115, (2013) (PubMed).

Target Details for Selectin E/CD62e

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Alternative Name: E-Selectin/CD62E (SELE Products)

Synonyms: SELE antibody, CD62E antibody, ELAM antibody, ELAM1 antibody, ESEL antibody, LECAM2 antibody, E-selectin antibody, Elam antibody, selectin E antibody, selectin, endothelial cell antibody, SELE antibody, Sele antibody

Background:

Synonyms: Elam, CD62E, E-selectin, CD62 antigen-like family member E, Endothelial leukocyte adhesion molecule 1, ELAM-1, Leukocyte-endothelial cell adhesion molecule 2, LECAM2, Sele

Background: Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.

Gene ID: 20339

UniProt: Q00690

Pathways: Thromboxane A2 Receptor Signaling