NLRC4 antibody (AA 941-990)

Catalog No. ABIN6735855

Product Details anti-NLRC4 Antibody

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Binding Specificity: AA 941-990

Reactivity: Human, Mouse, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Human NLRC4 / IPAF

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Mouse (86%) Rat, Guinea pig (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa941-990 of human NLRC4 (Q9NPP4, NP_067032). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%), Gibbon, Monkey (93%), Galago, Mouse (86%), Rat, Elephant, Bat, Guinea pig (80%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, WB (0.2 - 1 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for NLRC4

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Alternative Name: IPAF / NLRC4 (NLRC4 Products)

Background: Name/Gene ID: NLRC4
Family: Apoptosis

Synonyms: NLRC4, CARD12, CLANA, CLANB, CLANC, CLAND, CLAN, CLR2.1, Clan protein, CLAN1, Ice protease-activating factor, NOD-like receptor C4, ICE-protease activating factor, IPAF

Gene ID: 58484

NCBI Accession: NP_067032

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome