ACCN1 antibody (AA 481-530)

Catalog No. ABIN6735765

Product Details anti-ACCN1 Antibody

Target: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Binding Specificity: AA 481-530

Reactivity: Human, Rabbit, Horse, Monkey, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACCN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human ACCN1

Predicted Reactivity: Percent identity by BLAST analysis: Human, Rabbit, Horse (100%) Mouse, Rat, Bovine, Chicken (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa481-530 of human ASIC2 (Q16515-2, NP_899233). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Elephant, Bat, Rabbit, Horse (100%), Galago, Mouse, Rat, Bovine, Opossum, Turkey, Chicken (92%), Zebra finch (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for ACCN1

Target: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Alternative Name: ACCN1 / ASIC2 (ACCN1 Products)

Synonyms: ACCN antibody, ACCN1 antibody, ASIC2a antibody, BNC1 antibody, BNaC1 antibody, MDEG antibody, hBNaC1 antibody, ACIC2 antibody, Accn1 antibody, BNaC1a antibody, Mdeg antibody, BNC1k antibody, MDEG1 antibody, MDEG2 antibody, accn1 antibody, zASIC2 antibody, acid sensing ion channel subunit 2 antibody, acid-sensing (proton-gated) ion channel 2 antibody, ASIC2 antibody, Asic2 antibody, asic2 antibody

Background: Name/Gene ID: ASIC2
Subfamily: Sodium channel - amiloride-sensitive
Family: Ion Channel

Synonyms: ASIC2, ACCN1, ASIC2a, Brain sodium channel 1, Degenerin, ACCN, Acid-sensing ion channel 2, Mammalian degenerin homolog, MDEG, MDEG1, MDEG2, HBNaC1, BNaC1, MAMMALIAN DEGENERIN

Gene ID: 40

NCBI Accession: NP_899233

UniProt: Q16515

Pathways: Sensory Perception of Sound