GLI1 antibody (AA 601-700)
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- Target See all GLI1 Antibodies
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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Binding Specificity
- AA 601-700
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Reactivity
- Human, Mouse, Rat, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GLI1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human, Mouse, Pig, Rat
- Predicted Reactivity
- Dog,Cow,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GLI1
- Isotype
- IgG
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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Doxorubicin combined with low intensity ultrasound suppresses the growth of oral squamous cell carcinoma in culture and in xenografts." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 163, (2018) (PubMed).
: "Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 267, (2017) (PubMed).
: "Targeting GLI1 Suppresses Cell Growth and Enhances Chemosensitivity in CD34+ Enriched Acute Myeloid Leukemia Progenitor Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 4, pp. 1288-302, (2016) (PubMed).
: "Silibinin induces apoptosis through inhibition of the mTOR-GLI1-BCL2 pathway in renal cell carcinoma." in: Oncology reports, Vol. 34, Issue 5, pp. 2461-8, (2015) (PubMed).
: "Sonic hedgehog signaling may promote invasion and metastasis of oral squamous cell carcinoma by activating MMP-9 and E-cadherin expression." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 7, pp. 41, (2014) (PubMed).
: "Serotonin receptor 2C and insulin secretion." in: PLoS ONE, Vol. 8, Issue 1, pp. e54250, (2013) (PubMed).
: "Aberrant activation of hedgehog pathway in nasopharyngeal carcinoma." in: Clinical and experimental medicine, Vol. 13, Issue 4, pp. 315-22, (2013) (PubMed).
: "Curcumin suppresses malignant glioma cells growth and induces apoptosis by inhibition of SHH/GLI1 signaling pathway in vitro and vivo." in: CNS neuroscience & therapeutics, Vol. 19, Issue 12, pp. 926-36, (2013) (PubMed).
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Doxorubicin combined with low intensity ultrasound suppresses the growth of oral squamous cell carcinoma in culture and in xenografts." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 163, (2018) (PubMed).
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- Target
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
- Alternative Name
- GLI1 (GLI1 Products)
- Synonyms
- GLI antibody, Gli antibody, Gli-1 antibody, gli1.1 antibody, AV235269 antibody, Zfp-5 antibody, Zfp5 antibody, GLI family zinc finger 1 antibody, GLI family zinc finger 1 S homeolog antibody, GLI-Kruppel family member GLI1 antibody, GLI1 antibody, Gli1 antibody, gli1.S antibody, gli1 antibody
- Background
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Synonyms: GLI, Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLI, GLI1
Background: Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
- Gene ID
- 2735
- UniProt
- P08151
- Pathways
- Hedgehog Signaling, Dopaminergic Neurogenesis
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