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GLI1 antibody (AA 601-700)

GLI1 Reactivity: Human, Mouse, Rat, Pig WB, ELISA, FACS, IF (cc), IHC (p), IF (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN673374
  • Target See all GLI1 Antibodies
    GLI1 (Zinc Finger Protein GLI1 (GLI1))
    Binding Specificity
    • 15
    • 14
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-700
    Reactivity
    • 83
    • 53
    • 34
    • 16
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    Human, Mouse, Rat, Pig
    Host
    • 70
    • 13
    • 3
    • 1
    Rabbit
    Clonality
    • 66
    • 21
    Polyclonal
    Conjugate
    • 40
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLI1 antibody is un-conjugated
    Application
    • 53
    • 18
    • 15
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse, Pig, Rat
    Predicted Reactivity
    Dog,Cow,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GLI1
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Fan, Li, Liu, Cong, Zhao, Cao, Zheng: "Doxorubicin combined with low intensity ultrasound suppresses the growth of oral squamous cell carcinoma in culture and in xenografts." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 163, (2018) (PubMed).

    Yang, Wu, Feng, Huang, Liu, Liu, Chen: "Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 267, (2017) (PubMed).

    Long, Wang, Zheng, Lai, Xu, Hu, Lin, Zhang, Dong, Long, Tong, Liu: "Targeting GLI1 Suppresses Cell Growth and Enhances Chemosensitivity in CD34+ Enriched Acute Myeloid Leukemia Progenitor Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 4, pp. 1288-302, (2016) (PubMed).

    Ma, Liu, Zeng, Zhou, Guo, Xie, Yang, Zheng, Xu, Wang, Chang, He, Li: "Silibinin induces apoptosis through inhibition of the mTOR-GLI1-BCL2 pathway in renal cell carcinoma." in: Oncology reports, Vol. 34, Issue 5, pp. 2461-8, (2015) (PubMed).

    Fan, Wang, Zhao, Liu, Chen, Sun, Zheng: "Sonic hedgehog signaling may promote invasion and metastasis of oral squamous cell carcinoma by activating MMP-9 and E-cadherin expression." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 7, pp. 41, (2014) (PubMed).

    Zhang, Zhu, Zhou, Gao, Yuan, Han: "Serotonin receptor 2C and insulin secretion." in: PLoS ONE, Vol. 8, Issue 1, pp. e54250, (2013) (PubMed).

    Yue, Zhong, Pei, Xiao, Zhang, Jiang, Zhang, Chen, Yang, Dang, Chang: "Aberrant activation of hedgehog pathway in nasopharyngeal carcinoma." in: Clinical and experimental medicine, Vol. 13, Issue 4, pp. 315-22, (2013) (PubMed).

    Du, Feng, Wang, Piao, Cui, Chen, Lei, Sun, Liu, Wang, Li, Yang, Sun, Zhao, Jiang, Li, Jiang: "Curcumin suppresses malignant glioma cells growth and induces apoptosis by inhibition of SHH/GLI1 signaling pathway in vitro and vivo." in: CNS neuroscience & therapeutics, Vol. 19, Issue 12, pp. 926-36, (2013) (PubMed).

  • Target
    GLI1 (Zinc Finger Protein GLI1 (GLI1))
    Alternative Name
    GLI1 (GLI1 Products)
    Synonyms
    GLI antibody, Gli antibody, Gli-1 antibody, gli1.1 antibody, AV235269 antibody, Zfp-5 antibody, Zfp5 antibody, GLI family zinc finger 1 antibody, GLI family zinc finger 1 S homeolog antibody, GLI-Kruppel family member GLI1 antibody, GLI1 antibody, Gli1 antibody, gli1.S antibody, gli1 antibody
    Background

    Synonyms: GLI, Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLI, GLI1

    Background: Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.

    Gene ID
    2735
    UniProt
    P08151
    Pathways
    Hedgehog Signaling, Dopaminergic Neurogenesis
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