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CD3 antibody (mFluor™450)

Name: CD3 antibody (mFluor™450)
SKU: ABIN6731073
Price: 185.45 USD
Availability: InStock

GMP Grade CD3 Reactivity: Human FACS Host: Mouse Monoclonal UCHT1 mFluor™450

FACS

1 image

Catalog No. ABIN6731073

Datasheet as PDF

Target See all CD3 Antibodies

CD3
Reactivity
182

99

25

20

18

10

9

8

8

7

5

3

2

1
Human
Host
219

48

20

13

8
Mouse
Compatible Secondaries
Clonality
298

6
Monoclonal
Conjugate
95

40

33

25

23

11

8

6

6

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD3 antibody is conjugated to mFluor™450
Application
281

87

59

56

45

38

33

23

10

8

7

6

4

3

2

2

2

2

2

2

2

1

1
Flow Cytometry (FACS)

Purpose

CD3 mFluor™ 450 Antibody

Characteristics

The monoclonal UCHT1 clone recognizes CD3ε antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.

Purification

Purified

Purity

>95 %

Grade

GMP Grade

Immunogen

Thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor

Clone

UCHT1

Isotype

IgG1, kappa

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Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Storage Comment

2-8°C, Conjugated antibodies should never be frozen.
Target

CD3

Alternative Name

CD3 (CD3 Products)

Synonyms

CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody

Gene ID

916

NCBI Accession

NM_000733

UniProt

P07766

Pathways

TCR Signaling, Ubiquitin Proteasome Pathway