CD3 antibody (iFluor™700)

Catalog No. ABIN6731068

Product Details anti-CD3 Antibody (iFluor™700)

Target: CD3

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is conjugated to iFluor™700

Application: Flow Cytometry (FACS)

Purpose: CD3 iFluor™ 700 Antibody

Characteristics: CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: Human peripheral blood lymphocytes

Clone: OKT3

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD3

Target: CD3

Alternative Name: CD3 (CD3 Products)

Synonyms: CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody

Gene ID: 916

NCBI Accession: NM_000733

UniProt: P07766

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway