CD4 antibody (AA 231-330)

Catalog No. ABIN672936

Product Details anti-CD4 Antibody

Target: CD4

Binding Specificity: AA 231-330

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Hamster

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CD4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CD4 antibody (ABIN672936)

Wang, Johnson, He, Rong, Wong, Nigam, Behfar, Xu, Christman: "Humanized mouse model for assessing the human immune response to xenogeneic and allogeneic decellularized biomaterials." in: Biomaterials, Vol. 129, pp. 98-110, (2017) (PubMed).

Willett, Liu, Berke, Giannini, Schmid, Jia, Wang, Wang, Samson, Yu, Wang, Nawshad, Reinhardt: "Standardized Rat Model Testing Effects of Inflammation and Grafting on Extraction Healing." in: Journal of periodontology, Vol. 88, Issue 8, pp. 799-807, (2017) (PubMed).

Matsubara, Matsubara, Mori, Uchikura, Hamada, Fujioka, Hashimoto, Matsumoto: "Immune activation during the implantation phase causes preeclampsia-like symptoms via the CD40-CD40 ligand pathway in pregnant mice." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 39, Issue 6, pp. 407-14, (2017) (PubMed).

Ju, Xing, Yang, Zheng, Jia, Zhang, Ren: "An effective cytokine adjuvant vaccine induces autologous T-cell response against colon cancer in an animal model." in: BMC immunology, Vol. 17, Issue 1, pp. 31, (2016) (PubMed).

Tzeng, Wu, Peng, Cheng, Tang, Huang, Chu: "Hypercapnic acidosis prolongs survival of skin allografts." in: The Journal of surgical research, (2015) (PubMed).

Cheng, Guo, Qiao, Liu, Nie, Li, Wang, Jiang: "T cell immunohistochemistry refines lung transplant acute rejection diagnosis and grading." in: Diagnostic pathology, Vol. 8, pp. 168, (2013) (PubMed).

Zhang, Fei, Gao, Liu, Zhang: "The role of CXCR3 in the induction of primary biliary cirrhosis." in: Clinical & developmental immunology, Vol. 2011, pp. 564062, (2011) (PubMed).

Target Details for CD4

Target: CD4

Alternative Name: CD4 (CD4 Products)

Synonyms: cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody

Background:

Synonyms: L3T4, Ly-4, T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, CD4

Background: Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.

Gene ID: 12504

UniProt: P06332

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events