Interleukin 17a antibody (APC)
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- Target See all Interleukin 17a (IL17A) Antibodies
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This Interleukin 17a antibody is conjugated to APC
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Application
- Intracellular Flow Cytometry (ICFC)
- Clone
- TC11-18H10-1
- Isotype
- IgG1, kappa
- Top Product
- Discover our top product IL17A Primary Antibody
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- Application Notes
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
- Comment
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Matching Isotype Control: APC Rat IgG1, κ Isotype Control (ABIN7469823)
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Target
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
- Alternative Name
- IL-17A (IL17A Products)
- Synonyms
- CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
- Background
- Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,CTLA8,IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
- Gene ID
- 16171
- UniProt
- Q62386
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