Lipin 1 antibody (AA 241-340)

Catalog No. ABIN672846

Product Details anti-Lipin 1 Antibody

Target: Lipin 1 (LPIN1)

Binding Specificity: AA 241-340

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipin 1 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Lpin 1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Lipin 1

Target: Lipin 1 (LPIN1)

Alternative Name: Lpin1 (LPIN1 Products)

Synonyms: LPIN1 antibody, pap1 antibody, PAP1 antibody, 4631420P06 antibody, Kiaa0188 antibody, Lipin1 antibody, fld antibody, mKIAA0188 antibody, zgc:194552 antibody, zgc:194558 antibody, lipin1 antibody, lipin 1 antibody, phosphatidate phosphatase LPIN1 antibody, LPIN1 antibody, lpin1 antibody, LOC100539289 antibody, Lpin1 antibody

Background:

Synonyms: fld, Lipin1, Kiaa0188, mKIAA0188, 4631420P06, Phosphatidate phosphatase LPIN1, Fatty liver dystrophy protein, Lipin-1, Lpin1

Background: Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.

Gene ID: 14245

UniProt: Q91ZP3

Pathways: Monocarboxylic Acid Catabolic Process