PD-L1 antibody (PE)
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- Target See all PD-L1 Antibodies
- PD-L1 (CD274 (PD-L1))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This PD-L1 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Clone
- 10F-9G2
- Isotype
- IgG2b, kappa
- Top Product
- Discover our top product PD-L1 Primary Antibody
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- Application Notes
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
- Comment
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Matching Isotype Control: PE Rat IgG2b, κ Isotype Control (ABIN7469859)
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Target
- PD-L1 (CD274 (PD-L1))
- Alternative Name
- CD274/PD-L1 (PD-L1 Products)
- Synonyms
- B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
- Background
- B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
- Gene ID
- 60533
- UniProt
- Q9EP73
- Pathways
- Cancer Immune Checkpoints
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