ERCC3 antibody (AA 665-715)
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- Target See all ERCC3 Antibodies
- ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))
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Binding Specificity
- AA 665-715
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ERCC3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purpose
- Rabbit IgG polyclonal antibody for XPB detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
- Rabbit IgG polyclonal antibody for XPB detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- Purification
- Immunogen affinity purified.
- Immunogen
- E. coli-derived human XPB recombinant protein (Position: Q665-K715).
- Isotype
- IgG
- Top Product
- Discover our top product ERCC3 Primary Antibody
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- Application Notes
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Application details: Western blot|0.1-0.5 μg/mL Direct ELISA|0.1-0.5 μg/mL
- Comment
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))
- Alternative Name
- ERCC3 (ERCC3 Products)
- Synonyms
- BTF2 antibody, GTF2H antibody, RAD25 antibody, TFIIH antibody, XPB antibody, BTF2 p89 antibody, Ercc-3 antibody, wu:fc25f08 antibody, ERCC excision repair 3, TFIIH core complex helicase subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 3 antibody, excision repair cross-complementation group 3 antibody, ERCC3 antibody, Ercc3 antibody, ercc3 antibody
- Background
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Synonyms: General transcription and DNA repair factor IIH helicase subunit XPB, TFIIH subunit XPB, Basic transcription factor 2 89 kDa subunit, BTF2 p89, DNA excision repair protein ERCC-3, DNA repair protein complementing XP-B cells, TFIIH basal transcription factor complex 89 kDa subunit, TFIIH 89 kDa subunit, TFIIH p89, Xeroderma pigmentosum group B-complementing protein, ERCC3, XPB, XPBC
Background: XPB (xeroderma pigmentosum type B) is an ATP-dependent DNA helicase in humans that is a part of the TFIIH transcription factor complex. This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.
- Gene ID
- 2071
- UniProt
- P19447
- Pathways
- DNA Damage Repair
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