MVP antibody (AA 88-180)

Catalog No. ABIN671586

Product Details anti-MVP Antibody

Target: MVP (Major Vault Protein (MVP))

Binding Specificity: AA 88-180

Reactivity: Human, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVP antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Zebrafish (Danio rerio)

Cross-Reactivity (Details): Zebrafish

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRP

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MVP antibody (ABIN671586)

Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

Pan, Lin, Ma, Shen, Schachner: "Major vault protein promotes locomotor recovery and regeneration after spinal cord injury in adult zebrafish." in: The European journal of neuroscience, Vol. 37, Issue 2, pp. 203-11, (2013) (PubMed).

Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: LRP (MVP Products)

Synonyms: LRP antibody, VAULT1 antibody, 2310009M24Rik antibody, cb771 antibody, wu:fb52b05 antibody, wu:fc02g01 antibody, mvp antibody, MGC145641 antibody, Tb05.45E22.810 antibody, major vault protein antibody, major vault protein L homeolog antibody, putative major vault protein antibody, MVP antibody, Mvp antibody, mvp antibody, mvp.L antibody, Tc00.1047053510353.10 antibody, Tb927.5.4460 antibody, Tb10.70.0520 antibody, Tb10.70.5840 antibody, LMJF_05_0060 antibody

Background:

Synonyms: LRP, VAULT1, Major vault protein, MVP, Lung resistance-related protein

Background: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

Gene ID: 9961

UniProt: Q14764