SLC22A8 antibody (AA 31-110)
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- Target See all SLC22A8 Antibodies
- SLC22A8 (Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8))
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Binding Specificity
- AA 31-110
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Reactivity
- Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC22A8 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Mouse, Rat
- Predicted Reactivity
- Human,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human OAT-3
- Isotype
- IgG
- Top Product
- Discover our top product SLC22A8 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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Saponins extracted from Dioscorea collettii rhizomes regulate the expression of urate transporters in chronic hyperuricemia rats." in: Biomedicine & pharmacotherapy, Vol. 93, pp. 88-94, (2017) (PubMed).
: "Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1." in: Scientific reports, Vol. 6, pp. 32084, (2016) (PubMed).
: "Total saponins from Discorea nipponica ameliorate urate excretion in hyperuricemic mice." in: Planta medica, Vol. 80, Issue 15, pp. 1259-68, (2014) (PubMed).
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Saponins extracted from Dioscorea collettii rhizomes regulate the expression of urate transporters in chronic hyperuricemia rats." in: Biomedicine & pharmacotherapy, Vol. 93, pp. 88-94, (2017) (PubMed).
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- Target
- SLC22A8 (Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8))
- Alternative Name
- OAT-3 (SLC22A8 Products)
- Synonyms
- OAT3 antibody, Oat3 antibody, Roct antibody, OCT3 antibody, solute carrier family 22 member 8 antibody, solute carrier family 22 (organic anion transporter), member 8 antibody, SLC22A8 antibody, Slc22a8 antibody
- Background
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Synonyms: OAT3, Solute carrier family 22 member 8, Organic anion transporter 3, hOAT3, SLC22A8
Background: Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
- Gene ID
- 9376
- UniProt
- Q8TCC7
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