DPPA2 antibody

Catalog No. ABIN670656

Product Details anti-DPPA2 Antibody

Target: DPPA2 (Developmental Pluripotency Associated 2 (DPPA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPPA2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse DPPA2

Isotype: IgG

Application Details

Application Notes: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DPPA2

Target: DPPA2 (Developmental Pluripotency Associated 2 (DPPA2))

Alternative Name: DPPA2 (DPPA2 Products)

Synonyms: 2410088E07Rik antibody, C80932 antibody, D19Mgi18 antibody, ECAT15-2 antibody, CT100 antibody, PESCRG1 antibody, developmental pluripotency associated 2 antibody, ABC-type oliopeptide/dipeptide transporter, periplasmic binding protein DppA antibody, Dppa2 antibody, DPPA2 antibody, dppA2 antibody

Background:

Synonyms: Developmental Pluripotency Associated 2, developmental pluripotency associated gene2, PESCRG1, Pluripotent embryonic stem cell related protein 1, cancer/testis antigen 100, CT100, developmental pluripotency-associated gene 2, developmental pluripotency-associated protein 2, ECAT15-2, embryonic stem cell ESC associated transcript 15-2, PESCRG1, Pluripotent embryonic stem cell related protein 1, Pluripotent embryonic stem cell-related gene 1, Pluripotent embryonic stem cell-related gene 1 protein .

Background: SCRG1 (scrapie-responsive protein 1) is a 98 amino acid secreted protein that belongs to the SCRG1 family. The SCRG1 protein contains a 20-amino acid signal peptide, and is expressed abundantly in the central nervous system of human adult, but not at all in fetal brain. The protein is targeted to the Golgi apparatus and large dense-core vesicles/secretory granules in neurons. High levels of SCRG1 transcripts are also observed in testis and aorta. SCRG1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The SCRG1 protein may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. The human and mouse SCRG1 proteins share 83 % sequence identity. The SCRG1 gene is conserved in chimpanzee, cow, mouse, rat and chicken, and maps to human chromosome 4q34.1.

Gene ID: 151871

Pathways: Stem Cell Maintenance