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CDK8 antibody

CDK8 Reactivity: Human, Mouse, Rat WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN670266
  • Target See all CDK8 Antibodies
    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
    Reactivity
    • 80
    • 43
    • 28
    • 8
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 76
    • 3
    • 1
    Rabbit
    Clonality
    • 69
    • 11
    Polyclonal
    Conjugate
    • 40
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDK8 antibody is un-conjugated
    Application
    • 62
    • 29
    • 10
    • 10
    • 9
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDK8
    Isotype
    IgG
    Top Product
    Discover our top product CDK8 Primary Antibody
  • Application Notes
    WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Li, Tian, Ren, Chen, Wang, Ge, Wu, Sun, Liu, Xiao: "MicroRNA-101 is a potential prognostic indicator of laryngeal squamous cell carcinoma and modulates CDK8." in: Journal of translational medicine, Vol. 13, pp. 271, (2015) (PubMed).

  • Target
    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
    Alternative Name
    CDK8 (CDK8 Products)
    Synonyms
    K35 antibody, wu:fk95h11 antibody, cyclin dependent kinase 8 antibody, cyclin-dependent kinase 8 antibody, cyclin-dependent kinase 8 S homeolog antibody, Cyclin-dependent kinase 8 antibody, cyclin dependent kinase 19 antibody, CDK8 antibody, Cdk8 antibody, cdk8 antibody, cdk8.S antibody, cdk-8 antibody, CDK19 antibody
    Background

    Synonyms: Cyclin Dependent Kinase 8, Cell Division Kinase 8, Cell division protein kinase 8, K35, Mediator complex subunit CDK8, Mediator of RNA polymerase II transcription subunit CDK8, Protein kinase K35, CDK8_HUMAN, Cyclin-dependent kinase 8,.

    Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq, Jul 2008].

    Gene ID
    1024
    Pathways
    Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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