CCR2 antibody

Catalog No. ABIN670146

Product Details anti-CCR2 Antibody

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CCR-2

Isotype: IgG

Application Details

Application Notes: IHC-P (1:100-500),IF (p) (1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

References for anti-CCR2 antibody (ABIN670146)

Li, Pang, Yu, Wu, Guo, Zhang: "Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke." in: Brain : a journal of neurology, Vol. 136, Issue Pt 12, pp. 3578-88, (2013) (PubMed).

Target Details for CCR2

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Alternative Name: CCR-2 (CCR2 Products)

Synonyms: CC-CKR-2 antibody, CCR-2 antibody, CCR2A antibody, CCR2B antibody, CD192 antibody, CKR2 antibody, CKR2A antibody, CKR2B antibody, CMKBR2 antibody, MCP-1-R antibody, ACKR5 antibody, CKRX antibody, CRAM antibody, CRAM-A antibody, CRAM-B antibody, HCR antibody, Cc-ckr-2 antibody, Ccr2a antibody, Ccr2b antibody, Ckr2 antibody, Ckr2a antibody, Ckr2b antibody, Cmkbr2 antibody, mJe-r antibody, C-C motif chemokine receptor 2 antibody, C-C motif chemokine receptor like 2 antibody, chemokine (C-C motif) receptor 2 antibody, CCR2 antibody, CCRL2 antibody, Ccr2 antibody, LOC484790 antibody

Background:

Synonyms: C-C Chemokine receptor 2B, C C chemokine receptor type 2, C C CKR 2, CC chemokine receptor type 2, CC CKR 2, CCCKR2, CCR 2, CCR1L, CCR2A, CCR2B, CCR5L, CD192, CD192 antigen, Chemokine C C mot receptor 2, Chemokine CC Mot Receptor 2, CKR 2, CKR2, CKR2A, CKR2B, CMKBR2, MCP 1 R, MCP1 RECEPTOR, MCP1R, Monocyte chemoattractant protein 1 receptor, Monocyte Chemotactic Protein 1 Receptor, CCR2_HUMAN, C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CCR-2, CCR2, Monocyte chemoattractant protein 1 receptor, MCP-1-R.

Background: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].

Molecular Weight: 41kDa

Gene ID: 1231

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process