Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

EMP1 antibody (AA 101-160)

EMP1 Reactivity: Human, Mouse, Rat ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN670086
  • Target See all EMP1 products
    EMP1 (Epithelial Membrane Protein 1 (EMP1))
    Binding Specificity
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 101-160
    Reactivity
    Human, Mouse, Rat
    Host
    • 25
    • 1
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EMP1 antibody is un-conjugated
    Application
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Emp1
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    EMP1 (Epithelial Membrane Protein 1 (EMP1))
    Alternative Name
    EMP1 (EMP1 Products)
    Synonyms
    MGC84779 antibody, EMP1 antibody, si:ch73-90k17.2 antibody, CL-20 antibody, EMP-1 antibody, TMP antibody, I-8-09 antibody, ENP1MR antibody, epithelial membrane protein 1 antibody, epithelial membrane protein 1 L homeolog antibody, EMP1 antibody, emp1.L antibody, emp1 antibody, Emp1 antibody
    Background

    Synonyms: TMP, I-8-9, Epithelial membrane protein 1, EMP-1, Tumor-associated membrane protein, Emp1

    Background: Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.

    Gene ID
    13730
    UniProt
    P47801
You are here:
Support