CD24 antibody (AA 60-80)

Catalog No. ABIN669681

Product Details anti-CD24 Antibody

Target: CD24 (CD24 Molecule (CD24))

Binding Specificity: AA 60-80

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD24 antibody is un-conjugated

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody is produced with an immunogen contained within the propeptide region, it will only recognize the full length Signal transducer CD24 protein and not the mature form.

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD24 Propeptide

Isotype: IgG

Application Details

Application Notes: IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

References for anti-CD24 antibody (ABIN669681)

Khan, Czarnecka, Lewicki, Helbrecht, Brodaczewska, Koch, Zdanowski, Król, Szczylik: "Comparative Gene Expression Profiling of Primary and Metastatic Renal Cell Carcinoma Stem Cell-Like Cancer Cells." in: PLoS ONE, Vol. 11, Issue 11, pp. e0165718, (2016) (PubMed).

Wang, Zou, Deng, Fu, Li, Wu, Wang, Liu: "Characterization of sphere?forming cells with stem?like properties from the gastric cancer cell lines MKN45 and SGC7901." in: Molecular medicine reports, Vol. 10, Issue 6, pp. 2937-41, (2014) (PubMed).

Target Details for CD24

Target: CD24 (CD24 Molecule (CD24))

Alternative Name: Signal Transducer CD24 (CD24 Products)

Synonyms: CD24A antibody, Cd24a antibody, CD24 molecule antibody, CD24 antibody, Cd24 antibody

Background:

Synonyms: CD24A, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, CD24

Background: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.

Gene ID: 100133941

UniProt: P25063

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation