PICK1 antibody

Catalog No. ABIN6658111

Supplier Product No.: 200-301-g31

Product Details anti-PICK1 Antibody

Target: PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This PICK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Supplier Product No.: 200-301-g31

Supplier: Rockland

Purpose: PICK1 Antibody

Cross-Reactivity (Details): A BLAST analysis was used to suggest cross-reactivity with PICK1 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.

Purification: Anti-PICK1 Antibody was purified by Protein G chromatography.

Sterility: Sterile filtered

Immunogen: PICK1 Antibody was produced in mice by repeated immunizations raised against a fusion protein rat PICK1.

Clone: S20-8

Isotype: IgG2a

Application Details

Application Notes:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

IF_Microscopy_Dilution: 1.0-10 μg/mL

Western_Blot_Dilution: 1 μg/mL

Comment:

Anti-PICK1 Antibody is tested for use in WB, IHC and IP. Expect a band approximately ~45kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for PICK1

Target: PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

Alternative Name: PICK1 (PICK1 Products)

Background:

Synonyms: PRKCA, protein interacting with PRKCA1, PRKCA-binding protein, Protein interacting with C kinase 1, Protein kinase C-alpha-binding protein, Pick1, Prkcabp

Background: PRKCA-binding protein is a protein that is encoded by the Pick1 gene. The protein encoded by this gene contains a PSD domain, which interacts with protein kinase C, alpha. The protein functions as an adaptor that binds to and organizes subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, and non-voltage gated sodium channels. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner.

Gene Name: Pick1